By Jim Foote
X-Men: Apocalypse is the third in the NEW trilogy, following up First Class and Days of Future Past. What the X-Franchise is good at pulling off is they take a particular time period and or storyline from the comics, turn it on its head, and run with it. They make some changes to fit their existing timeline(s), but nothing sacrilegious.
To keep it short, sweet, and spoiler free since '93 (only a few of you will get that, and you deserve a high five), I'm going to leave out a few things that would otherwise... not necessarily spoil you, but may give you clues along the road to spoiler-ification.